Imaging drug targets inside the cell’s “black box”

What’s actually going on inside the cell? How can drug discovery researchers accurately assess the exposure of a given drug to potential intracellular targets?
Until now, traditional reliance on metrics such as plasma concentration couldn’t account for intracellular phenomena such as the tendency of drug molecules to bind to organelles. So exposure/response comparisons were often fatally flawed.
A novel approach — drugSIMSTM — tackles the problem using advanced imaging instrumentation within a specialized workflow. Result: a proven new solution. And it’s all created via a new kind of academic/industry collaboration.
To discover more, read our new pharmacokinetics paper.

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