Imaging drug targets inside the cell’s “black box”
What’s actually going on inside the
cell? How can drug discovery
researchers accurately assess the
exposure of a given drug to
potential intracellular targets?
Until now, traditional reliance on metrics such as plasma concentration
couldn’t account for intracellular phenomena such as the tendency of
drug molecules to bind to organelles. So exposure/response
comparisons were often fatally flawed.
A novel approach — drugSIMSTM
— tackles the problem using
advanced imaging instrumentation within a specialized workflow.
Result: a proven new solution. And it’s all created via a new kind of
academic/industry collaboration.
To discover more, read our new pharmacokinetics paper.
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